FPGEE for National Association of Boards of Pharmacy (NABP) Practice Exam

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Which of the following conditions is NOT a side effect of carbamazepine?

  1. Thrombocytopenia

  2. Increased appetite

  3. Hyponatremia

  4. Dermatological reactions

The correct answer is: Increased appetite

Carbamazepine is commonly known for its various side effects, among which thrombocytopenia, hyponatremia, and dermatological reactions are well-documented. Thrombocytopenia refers to a decrease in blood platelets, which can lead to increased bleeding risk. Hyponatremia, or low sodium levels in the blood, is a notable concern with carbamazepine therapy, as it can cause neurological complications. Dermatological reactions, including skin rashes and possibly more severe reactions like Stevens-Johnson syndrome, are also associated with its use. In contrast, increased appetite is not recognized as a typical side effect of carbamazepine. While other medications may have this effect, carbamazepine is more likely to be associated with weight gain, but not specifically with an increased appetite. Thus, recognizing that increased appetite does not align with the expected side effects of carbamazepine supports the conclusion that it is not a side effect.