FPGEE for National Association of Boards of Pharmacy (NABP) Practice Exam

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What is the most common pathogen associated with meningitis?

  1. Escherichia coli

  2. Neisseria meningitidis

  3. Staphylococcus aureus

  4. Clostridium difficile

The correct answer is: Neisseria meningitidis

Neisseria meningitidis is recognized as the most common pathogen associated with meningitis, particularly in children and young adults. This bacterium is a Gram-negative diplococcus and is a leading cause of bacterial meningitis worldwide. It has the ability to rapidly invade the bloodstream and central nervous system, leading to severe clinical manifestations such as fever, neck stiffness, and altered mental status. Meningococcal disease can manifest as meningitis or septicemia, and its transmission often occurs through respiratory droplets or close contact. Vaccination has become an essential preventive measure against N. meningitidis, especially for at-risk populations, highlighting the importance of understanding this pathogen in the context of public health and clinical practice. By focusing on N. meningitidis and its impact on meningitis, it becomes clear that recognition and timely treatment are crucial in managing this serious condition, which also underscores the importance of maintaining awareness of its prevalence as a leading cause of bacterial meningitis.